Betterage Journal

After colon cancer: Exercise joins follow-up care.

CHALLENGE provides important evidence for a supported exercise programme after surgery and chemotherapy.

CHALLENGE randomly assigned 889 people after surgery and adjuvant chemotherapy for colon cancer to three years of supported exercise or health information. Participants had stage III or high-risk stage II disease.

Nach fünf Jahren lebten 80,3 Prozent der Trainingsgruppe ohne Rückfall, neuen Primärtumor oder Tod; in der Vergleichsgruppe waren es 73,9 Prozent. Der absolute Unterschied betrug 6,4 Prozentpunkte. Auch die Ergebnisse zum Gesamtüberleben fielen zugunsten des Trainings aus.

This was a programme supported by exercise professionals over several years. Musculoskeletal adverse events were more frequent: 18.5% versus 11.5%. Support and an appropriate workload therefore matter when interpreting the result.

The trial addresses this particular follow-up setting. It does not show that exercise prevents every cancer or that any app programme delivers the same benefit. It does show why movement deserves attention after cancer treatment.

What this does not establish

Kein Ersatz für Krebstherapie oder Nachsorge; nicht auf alle Tumorarten und Krankheitsstadien übertragbar.

Original sources

  1. CHALLENGE: NEJM, 01.06.2025
  2. Canadian Cancer Trials Group: CHALLENGE, 01.06.2025

Editorial analysis by Betterage. Not personal medical advice. The article publication date may differ from the date of the cited study.

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After colon cancer: Exercise joins follow-up care. · Betterage Journal